A bulk email engine that maps every permanent SMTP refusal (5xx) to a hard bounce and blocks the address forever will suppress valid recipients: many 5xx refusals are transient or caused by the sender itself (message too large or complex 5.3.4, the sender domain failing its own DMARC/SPF 5.7.26/5.7.23, reputation or throttling blocks). Unbounce is usually rate limited, so the damage cannot be undone. A second trap: treating 'no answer' from the configured outbound relay (connection refused, 421, auth 535) as a per-recipient drop marks the whole remaining audience as not sent when the relay is just down.