Simplifying working Caesar cipher

I'm learning Python 3 at the moment, so to test the skills I've learned, I am trying the puzzles at Python Challenge.

I've created some code to solve the 2nd puzzle here. it works, but I think that the way I've done it is very convoluted. Any suggestions on how to solve the puzzle in a simpler way?

(The code basically needs to substitute each letter in a message to the letter 2 spaces to the right of it, such as E->G.)

import string
alphabet = string.ascii_lowercase
letter=0
replaceLetter = 2
times=1
message = input()
newMessage=''
while times < 26:
    newMessage = message.replace(alphabet[letter], str(replaceLetter)+',')
    message = newMessage
    letter = letter + 1
    replaceLetter = replaceLetter + 1
    time = times + 1
    if letter == 26:
        times = 0
        break
newMessage = message.replace('26'+',', 'a')
message = newMessage
newMessage = message.replace('27'+',', 'b')
message = newMessage
number = 25
message = newMessage
while times < 26:
    newMessage = message.replace(str(number)+',', str(alphabet[number]))
    message = newMessage
    letter = letter + 1
    number = number - 1
    time = times + 1
    if number == -1:
        times = 0
        break
print(newMessage)

I would define a shift function that shifted the letters like so:

from string import whitespace, punctuation

def shift(c, shift_by = 2):
    if c in whitespace + punctuation: return c

    upper_ord, lower_ord, c_ord = ord('A'), ord('a'), ord(c)
    c_rel = (c_ord - lower_ord) if c_ord >= lower_ord else (c_ord - upper_ord)
    offset = lower_ord if c_ord >= lower_ord else upper_ord
    return chr(offset + (c_rel + shift_by) % 26)

Then, to translate a message:

msg = 'a quick brown fox jumped over the lazy dog'
encoded_msg = ''.join(shift(l) for l in msg)

Alternatively, combine Mark Tolonen's maketrans suggestion with g.d.d's deque suggestion to get:

import string
from collections import deque

alphabet = string.ascii_lowercase
alphabet_deque = deque(alphabet)
alphabet_deque.rotate(-2)
rotated_alphabet = ''.join(alphabet_deque)
tbl = string.maketrans(alphabet, rotated_alphabet)

Then, later in the code:

msg = 'a quick brown fox jumped over the lazy dog'
encoded_msg = string.translate(msg, tbl)

This second method only works for lowercase letters, but you can always create two separate translation tables -- one for uppercase letters and another for lowercase letters -- to account for case.

Offtopic note: sometimes I wish Python had Smalltalk-like cascaded message sends. Ah well, one can dream.

StackExchange Code Review Q#6493, answer score: 3